@article{Moura Filho_GuimarĂ£es Grana_Carvalho Maron_Rodrigues Ferreira Rocha de Alencar_Vianei Real Antonio_Chicre Bandeira de Melo_2017, title={Pyoderma Gangrenosum associated with Paroxysmal Nocturnal Haemoglobinuria}, volume={75}, url={https://revista.spdv.com.pt/index.php/spdv/article/view/773}, DOI={10.29021/spdv.75.2.773}, abstractNote={<p>Pyoderma gangrenosum is a chronic neutrophilic dermatosis with no established etiology. It is often associated with systemic diseases such as inflammatory rheumatic diseases, inflammatory bowel diseases, malignant neoplasms and haematological diseases including nocturnal paroxysmal hemoglobinuria. It presents as ulcerated and painful skin lesions with rapid and progressive evolution, mainly in the lower limbs. Ulcerations may arise spontaneously or induced by trauma (pathergy phenomenon). The period between the onset of the lesions and the diagnosis is usually prolonged. The diagnosis is based on clinical data and confirmed after the exclusion of other causes of cutaneous ulcerations. We report a case of Pyoderma gangrenosum in the left upper limb with onset after a traumatic event in a patient with nocturnal paroxysmal hemoglobinuria.</p&gt;}, number={2}, journal={Journal of the Portuguese Society of Dermatology and Venereology}, author={Moura Filho, Francisco Ronaldo and GuimarĂ£es Grana, Aline and Carvalho Maron, Suzi Marla and Rodrigues Ferreira Rocha de Alencar, Raquel and Vianei Real Antonio, Bruno and Chicre Bandeira de Melo, Patricia}, year={2017}, month={Jul.}, pages={173-177} }