TY - JOUR AU - Katarina Kieselová AU - Luís Soares-de-Almeida PY - 2020/07/14 Y2 - 2024/03/29 TI - Dermatoses with Minimal Histological Changes: Making the Invisible Visible JF - Journal of the Portuguese Society of Dermatology and Venereology JA - SPDV VL - 78 IS - 2 SE - Review Articles DO - 10.29021/spdv.78.2.1206 UR - https://revista.spdv.com.pt/index.php/spdv/article/view/1206 AB - Skin biopsies remain an indispensable tool for aiding dermatologists in accurate diagnosis and treatment. However, some clinically evident skin diseases show histological picture resembling normal skin when examined after preparation with hematoxylin and eosin (H&E). In order to establish the correct diagnosis, clinicopathological correlation is essential, together with further investigations such as special stains and immunohistochemistry techniques. Hereby, we discuss the most relevant of these “invisible” dermatoses on H&E, and include strategy for approaching such cases. ER -