TY - JOUR AU - Virginia Coelho de Sousa AU - Rita Ramos Pinheiro AU - Filipa Rocha Páris AU - Margarida Apetato AU - Gabriela Marques Pinto PY - 2018/01/26 Y2 - 2024/03/28 TI - Auto-immune Photodermatoses Part I – Pathogenesis and Diagnosis JF - Journal of the Portuguese Society of Dermatology and Venereology JA - SPDV VL - 75 IS - 4 SE - Review Articles DO - 10.29021/spdv.75.4.876 UR - https://revista.spdv.com.pt/index.php/spdv/article/view/876 AB - The autoimmune photodermatoses are a group of heterogeneous idiopathic dermatoses physiopathologically characterized by underexplored immune mechanisms, usually involving an immune reaction against an unknown antigen. This group includes five different clinical entities – polymorphous light eruption, actinic prurigo, hydroa vacciniforme, chronic actinic dermatitis, solar urticaria - some potentially severe with great impact in patients’ quality of life. The pathogenesis of the autoimmune photodermatosis seems to be realated with the formation of photoallergens in response to sunlight. The hypersensibility mechanism varies between the different diseases. The diagnosis depends on the recognition of the clinical presentation. Phototests confirm the diagnosis and allow the determination of the responsible radiation and limiar dose of induction. In an era where photodermatology has been losing its importance, we propose to revise the pathogenesis and diagnosis of autoimmune photodermatoses. ER -