Cutaneous Metastasis as the Presenting Sign of Urothelial Carcinoma

Tânia Rita  Moreno de Oliveira Fernandes; Ricardo Santana de Lima; Ana Kívia Silva Matias; Leonardo Pereira de Souza Alves; Marcus Vinícius Solano Ferreira de Souza

doi:10.29021/spdv.78.3.1203

Tânia Rita Moreno de Oliveira Fernandes Sanitary Physician, Dermatologist, and Hansenologist, Master and Doctor of Science from UNIFESP/EPM, Coordinator of the School of Medicine at the Universidade Federal do Vale do São Francisco (Univasf), Adjunct Professor of Dermatology at Univasf, Petrolina, Pernambuco, Brazil https://orcid.org/0000-0002-7061-2825
Ricardo Santana de Lima Biologist, IB/UFBA, Doctor in Pathology, FAMED-UFBA/CPqGM-Fiocruz-BA, Adjunct Professor III, Univasf, Professor of the Post-Graduate Program in Materials Science and Manager of Teaching and Research at the HU-Univasf/Ebserh, Petrolina, Pernambuco, Brazil https://orcid.org/0000-0002-1279-3445
Ana Kívia Silva Matias Medical student at Univasf, Petrolina, Pernambuco, Brazil https://orcid.org/0000-0002-2816-3528
Leonardo Pereira de Souza Alves Medical student at Univasf, Petrolina, Pernambuco, Brazil https://orcid.org/0000-0001-8413-1603
Marcus Vinícius Solano Ferreira de Souza Medical student at Univasf, Petrolina, Pernambuco, Brazil https://orcid.org/0000-0002-5919-356X

DOI: https://doi.org/10.29021/spdv.78.3.1203

Keywords: Carcinoma, Transitional Cell, Skin Neoplasms/secondary, Urinary Bladder Neoplasms

Abstract

Cutaneous metastases of visceral neoplasms are rare conditions, and urothelial or transitional cell carcinomas are responsible for less than 1% of cases. We report the case of a 50-year-old male patient who progressively developed multiple cutaneous nodules on his head, abdomen, axilla, and groin, some with ulceration. Skin biopsy and immunohistochemistry were consistent with cutaneous metastasis of urothelial carcinoma. Computed tomography scan revealed generalized metastasis in internal organs. In this rare case, cutaneous metastases were the presenting sign of the disease and, as reported, a sign of bad prognosis.

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