Acquired Leukoderma in a Patient with Allergic Contact Dermatitis to FreeStyle Libre®

C. S. Queirós; M. I. Alexandre; P. M. Garrido; L. Soares de Almeida; T. Correia; P. Filipe

doi:10.29021/spdv.78.4.1272

C. S. Queirós Serviço de Dermatologia, Hospital de Santa Maria, Centro Hospitalar e Universitário de Lisboa Norte, Lisboa, Portugal https://orcid.org/0000-0002-0893-628X
M. I. Alexandre Serviço de Endocrinologia, Diabetes e Metabolismo, Hospital de Santa Maria, Centro Hospitalar e Universitário de Lisboa Norte, Lisboa, Portugal
P. M. Garrido Serviço de Dermatologia, Hospital de Santa Maria, Centro Hospitalar e Universitário de Lisboa Norte, Lisboa, Portugal
L. Soares de Almeida Serviço de Dermatologia, Hospital de Santa Maria, Centro Hospitalar e Universitário de Lisboa Norte, Lisboa, Portugal; Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal https://orcid.org/0000-0003-4026-6105
T. Correia Serviço de Dermatologia, Hospital de Santa Maria, Centro Hospitalar e Universitário de Lisboa Norte, Lisboa, Portugal
P. Filipe Serviço de Dermatologia, Hospital de Santa Maria, Centro Hospitalar e Universitário de Lisboa Norte, Lisboa, Portugal https://orcid.org/0000-0001-6917-527X

DOI: https://doi.org/10.29021/spdv.78.4.1272

Keywords: Acrylates/adverse effects, Blood Glucose Self-Monitoring, Dermatitis, Allergic Contact/etiology, Hypopigmentation/ chemically induced

Abstract

In the past few years, the glucose sensor FreeStyle Libre® has been associated with several cases of allergic contact dermatitis. The allergen responsible for most of these cases is isobornyl acrylate, a substance present within the sensor that migrates through the adhesive, thereby reaching the skin. Acquired leukoderma, which may occur in an area previously affected by allergic contact dermatitis, has been described in several medical devices with adhesives. However, until the present, only one case of leukoderma induced by allergic contact dermatitis to FreeStyle Libre® has been described. We report the case of a 41-year-old woman with diabetes mellitus type 1, who developed leukoderma in association with allergic contact dermatitis to this glucose sensor.

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