ATYPICAL REVERSE REACTION IN A MULTIBACILLARY PATIENT

Abstract

Leprosy is an infectious disease caused by Mycobacterium leprae that primarily affects the skin and/or peripheral nerves. It can have periods of acute reactions known as type 1 or reverse and type 2 or erythema nodosum. These reactions reflect the immune-mediated inflammatory process involving different mechanisms of hypersensitivity. The type 1 reaction corresponds to a sudden increase in cell-mediated immunity is more common in paucibacillary forms of the disease and type 2 reaction is recognized as changes in humoral immunity, is more common in multibacillary. This article aims to demonstrate a case of reverse reaction in a multibacillary patient.

KEYWORDS – Leprosy, multibacillary; Mycobacterium leprae.