Carcinoma Cuniculatum with Bone Invasion Mimicking a Viral Wart

  • Isabela Guerra Residente de Dermatologia / Resident of Dermatology in Federal University of Juiz de Fora Teaching Hospital – Juiz de Fora, Brazil
  • Hisabella Lorena Porto Simões Residente de Dermatologia / Resident of Dermatology in Federal University of Juiz de Fora Teaching Hospital – Juiz de Fora, Brazil
  • Marcella Amaral Horta Barbosa Vieira Dermatologist in private clinic, Lana’s Clinic – Juiz de Fora, Brazil
  • Maria Christina Marques Nogueira Castañon Professor titular e pesquisador / Full professor and Reseacher in Institute of Biological Sciences of the Federal University of Juiz de Fora – Juiz de Fora, Brazil
Keywords: Carcinoma, Squamous Cell, Carcinoma, Verrucous, Neoplasm Invasiveness, Warts


Carcinoma cuniculatum is a rare variant of low-grade and well-differentiated squamous cell carcinoma. It is a locally invasive tumor, although it has low metastatic potential. It was originally described in the plantar region but may exceptionally appear in other locations. It predominates in middle-aged men and presents clinically as an exophytic, solitary, painful tumor, with insidious growth. Histologically, this tumor simulates a variety of benign dermatoses and may require several biopsies for the correct diagnosis. It is often misdiagnosed as a viral wart, due to the clinical similarity and the indolent course. The treatment of choice is surgical excision due to the high risk of recurrence and locally aggressive behavior. Amputation can be performed in cases of deep tissue invasion. We present a case of carcinoma cuniculatum in which the late diagnosis favored the invasion of the underlying bone, resulting in amputation of the affected finger.


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How to Cite
Guerra, I., Porto Simões, H. L., Horta Barbosa Vieira, M. A., & Marques Nogueira Castañon, M. C. (2021). Carcinoma Cuniculatum with Bone Invasion Mimicking a Viral Wart. Journal of the Portuguese Society of Dermatology and Venereology, 79(3), 265-268.
Case Reports