PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
Introduction: Follicular lymphoma is the most common B-cell lymphoma to occur as a primary tumor of skin.
Case report: The case of a 69-year-old caucasian female patient, with a 1 year history of a painless nodule, localized in the frontal region, which had been observed several times on urgency room. On examination, we observed a nontender nodule, 3x2 cm, localized in the frontal region with small papules at the periphery. Histopathologic examination of a biopsy from the nodule was suggestive of follicular lymphoma.
Immunophenotyping: CD20+, CD3-, CD5-, CD10+, Bcl2+ in rare cells. The patient was observed by Hematology/ Oncology and the staging was negative and a course of palliative chemotherapy with R-CHOP, followed by radiotherapy was given. During a follow-up of 6 months there wasn´t any evidence of recurrences.
Conclusion: This case report intends emphasize the relevance of educate the doctors for the diagnosis of this disease.
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