PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER

  • Cristina Resende Interno do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Serviço de Dermatologia e Venereologia, Hospital de Braga, Braga, Portugal
  • Catarina Araújo Interno do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Serviço de Dermatologia e Venereologia, Hospital de Braga, Braga, Portugal
  • R. Santos Interno do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Serviço de Dermatologia e Venereologia, Hospital de Braga, Braga, Portugal
  • Celeste Brito Chefe de Serviço, Diretora do Serviço de Dermatologia e Venereologia/Consultant Chief, Head of Department of Dermatology and Venereology. Serviço de Dermatologia e Venereologia, Hospital de Braga, Braga, Portugal
Keywords: Lymphoma, follicular, Skin neoplasms

Abstract

Introduction: Follicular lymphoma is the most common B-cell lymphoma to occur as a primary tumor of skin.

Case report: The case of a 69-year-old caucasian female patient, with a 1 year history of a painless nodule, localized in the frontal region, which had been observed several times on urgency room. On examination, we observed a nontender nodule, 3x2 cm, localized in the frontal region with small papules at the periphery. Histopathologic examination of a biopsy from the nodule was suggestive of follicular lymphoma.

Immunophenotyping: CD20+, CD3-, CD5-, CD10+, Bcl2+ in rare cells. The patient was observed by Hematology/ Oncology and the staging was negative and a course of palliative chemotherapy with R-CHOP, followed by radiotherapy was given. During a follow-up of 6 months there wasn´t any evidence of recurrences.

Conclusion: This case report intends emphasize the relevance of educate the doctors for the diagnosis of this disease.

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References

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How to Cite
Resende, C., Araújo, C., Santos, R., & Brito, C. (1). PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER. Journal of the Portuguese Society of Dermatology and Venereology, 72(4), 587-591. https://doi.org/10.29021/spdv.72.4.334
Section
Case Reports