FUMARIC ACID ESTERS - A THERAPEUTIC OPTION IN PLAQUE PSORIASIS
Abstract
Fumaric acid esters are licensed for the treatment of psoriasis in Germany, since 1994. They are effective, safe and economical when compared with other systemic therapies used in moderate to severe plaque-type psoriasis. Fumarate esters have promising potential not only for the treatment of psoriasis but also for other less frequent dermatological conditions. The aim of this article is to review the mechanisms of action, indications and contraindications for this therapy.
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