PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE

  • Sandrina Carvalho Interna de Dermatovenereologia/Resident, Dermatology and Venereology, Serviço de Dermatologia, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
  • Tiago Torres Assistente Hospitalar de Dermatovenereologia/Consultant Dermatology and Venereology, Serviço de Dermatologia, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
  • Manuela Selores Chefe de Serviço, Directora do Serviço de Dermatologia/Head of Dermatology and Venereology Department, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal

Abstract

Psoriasis is a chronic systemic T-cell-mediated inflammatory disease with high morbidity. Psoriasis’s investigation has been intense, improving knowledge on physiopathology and leading to new biologic therapies for moderate and severe psoriasis’s treatment. This review will focus the present and the future of anti-cytokine therapies, beside the class of tumor necrosis factor-α (TNF-α) blockers.

KEYWORDS – Antibodies, Monoclonal; Biological agents; Dermatologic agents; Psoriasis.

Downloads

Download data is not yet available.

Author Biographies

Sandrina Carvalho, Interna de Dermatovenereologia/Resident, Dermatology and Venereology, Serviço de Dermatologia, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
Interna de Dermatovenereologia/Resident, Dermatology and Venereology, Serviço de Dermatologia, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
Tiago Torres, Assistente Hospitalar de Dermatovenereologia/Consultant Dermatology and Venereology, Serviço de Dermatologia, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
Assistente Hospitalar de Dermatovenereologia/Consultant Dermatology and Venereology, Serviço de Dermatologia, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
Manuela Selores, Chefe de Serviço, Directora do Serviço de Dermatologia/Head of Dermatology and Venereology Department, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
Chefe de Serviço, Directora do Serviço de Dermatologia/Head of Dermatology and Venereology Department, Centro Hospitalar do Porto, Hospital Santo António, Porto, Portugal
Published
2013-01-13
How to Cite
Carvalho, S., Torres, T., & Selores, M. (2013). PSORIASIS TREATMENT WITH BIOLOGICS: BEYOND TUMOR NECROSIS FACTOR α INIHIBITORS – THE PRESENT AND THE FUTURE. Journal of the Portuguese Society of Dermatology and Venereology, 70(3), 299. https://doi.org/10.29021/spdv.70.3.5
Section
Review Articles