Lobomycosis

Abstract

Lobomycosis or Jorge Lobo's disease is a chronic granulomatous infection, caused by the traumatic implantation of the fungus Lacazia loboi, that affects the skin and subcutis. This dermatosis is typical of tropical and subtropical regions and affects mainly active adult males working in the forest, but it has also been already diagnosed in dolphins. The lesions primarily involve exposed skin areas , such as the auricle, and the upper and lower limbs. Keilodal lesions are the main clinical presentation. Surgical removal is the therapeutic procedure of choice in the initial cases, whereas itraconazole and clofazimine, alone or in combination, may be used in disseminated lesions.