Facial Hyperpigmentation Induced by Combination Therapy with Olmesartan Medoxomil- -Hydrochlorothiazide

Miguel Costa-Silva, Artur César, Nuno P. Gomes, Margarida S. Fernandes, Filomena Azevedo

Abstract


Photodistributed hyperpigmentation has been associated with several drugs. We describe a 69-year-old woman who developed facial skin hyperpigmentation starting after treatment with a combination of olmesartan medoxomil and hydrochlorothiazide and improving following its withdrawal, suggesting drug-induced dyspigmentation. Olmesartan
medoxomil-hydrochlorothiazide should be added to the list of drugs that can induce photodistributed cutaneous hyperpigmentation.


Keywords


Face; Hydrochlorothiazide; Hyperpigmentation; Photosensitivity Disorders; Olmesartan Medoxomil

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DOI: http://dx.doi.org/10.29021/spdv.76.3.905

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