Facial Hyperpigmentation Induced by Combination Therapy with Olmesartan Medoxomil- -Hydrochlorothiazide

  • Miguel Costa-Silva Interno do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Centro Hospitalar São João, EPE, Porto, Portugal
  • Artur César Especialista de Dermatologia e Venereologia/ Consultant, Dermatology and Venereology, Centro Hospitalar São João, EPE, Porto, Portugal
  • Nuno P. Gomes Interno do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Centro Hospitalar São João, EPE, Porto, Portugal
  • Margarida S. Fernandes Interna do Internato Complementar de Anatomia Patológica/Resident, Anatomic Pathology, Centro Hospitalar São João, EPE, Porto, Portugal
  • Filomena Azevedo Diretora do Serviço de Dermatologia e Venereologia/Head of the Dermatology and Venereology Department, Centro Hospitalar São João, EPE, Porto, Portugal
Keywords: Face, Hydrochlorothiazide, Hyperpigmentation, Photosensitivity Disorders, Olmesartan Medoxomil

Abstract

Photodistributed hyperpigmentation has been associated with several drugs. We describe a 69-year-old woman who developed facial skin hyperpigmentation starting after treatment with a combination of olmesartan medoxomil and hydrochlorothiazide and improving following its withdrawal, suggesting drug-induced dyspigmentation. Olmesartan
medoxomil-hydrochlorothiazide should be added to the list of drugs that can induce photodistributed cutaneous hyperpigmentation.

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Published
2018-10-05
How to Cite
Costa-Silva, M., César, A., P. Gomes, N., S. Fernandes, M., & Azevedo, F. (2018). Facial Hyperpigmentation Induced by Combination Therapy with Olmesartan Medoxomil- -Hydrochlorothiazide. Journal of the Portuguese Society of Dermatology and Venereology, 76(3), 321-323. https://doi.org/10.29021/spdv.76.3.905
Section
Case Reports