Lepromatous Leprosy: Report of a Histoid-Like Case

Ana Carolina Serra Rodrigues, Danielle Carvalho Quintella, Felipe Tavares Rodrigues, Mercedes Prates Pockstaller, José Augusto da Costa Nery


Histoid leprosy, described by Wade in 1963, represents an atypical variant of lepromatous leprosy, with its own clinical and pathological features. In the past, it was considered a marker of drug resistance and relapse. It presents as keloid-like plaque or nodular lesions. Optical microscopy shows few foamy macrophages and numerous alcohol-acid-resistant bacilli and an infiltrate composed predominantly of spindle cells, which can mimic fibrohistiocytic neoplasms. We report a case of lepromatous leprosy with lesions clinically compatible with the histoid variant in order to demonstrate and reinforce the clinical polymorphism of this type of Hansen’s disease and raise awareness for the need of an early diagnosis and treatment, therefore with the interruption of the transmission chain and reduction of the occurrence of irreversible leprosy-related disability.


Leprosy, Lepromatous; Skin

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DOI: http://dx.doi.org/10.29021/spdv.77.1.962


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