MERKEL CELL CARCINOMA – REPORT OF 7 CASES

  • Rita Cabral Interna do Internato Complementar de Dermatologia e Venereologia / Resident, Dermatology and Venereology - Serviço de Dermatologia e Venereologia, Centro Hospitalar Universitário de Coimbra, Portugal
  • Ana Brinca Assistente Hospitalar de Dermatologia e Venereologia/Consultant, Dermatology and Venereology - Serviço de Dermatologia e Venereologia, Centro Hospitalar Universitário de Coimbra, Portugal
  • Ricardo Vieira Assistente Hospitalar de Dermatologia e Venereologia/Consultant, Dermatology and Venereology - Serviço de Dermatologia e Venereologia, Centro Hospitalar Universitário de Coimbra, Portugal
  • Angelina Mariano Assistente Hospitalar Graduada de Dermatologia e Venereologia / Graduated Consultant Dermatology and Venereology - Serviço de Dermatologia e Venereologia, Centro Hospitalar Universitário de Coimbra, Portugal
  • Óscar Tellechea Chefe de Serviço e Professor de Dermatologia e Venereologia / Consultant Chief and Professor, Dermatology and Venereology - Serviço de Dermatologia e Venereologia, Centro Hospitalar Universitário de Coimbra, Portugal
  • Américo Figueiredo Chefe de Serviço, Director do Serviço de Dermatologia e Venereologia / Consultant Chief, Head of Department of Dermatology and Venereology Serviço de Dermatologia e Venereologia, Centro Hospitalar Universitário de Coimbra, Portugal
Keywords: Carcinoma, Merkel cell, Skin neoplasms, neuroendocrine

Abstract

Introduction: Merkel cell carcinoma is a rare, aggressive cutaneous neuroendocrine carcinoma that affects primarily elderly people. Patients present with a rapidly growing nodule, preferably located at the head, neck and limbs. Merkel cell carcinoma as a propensity for local recurrence and regional lymph node metastases and wide local excision is the initial consensual approach. The role of lymph node dissection, radiation therapy and chemotherapy is not yet clearly established. 

Material and Methods: The aim of this retrospective study was to evaluate Merkel cell carcinoma patients followed in our department between the years 2000 and 2009, regarding sex, age, race, clinical features, location, stage, associated malignancies, treatment and evolution.  Results: Our data are consistent with the literature, namely regarding age, associated lymphoproliferative disease and high local recurrence and mortality rates.

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How to Cite
Cabral, R., Brinca, A., Vieira, R., Mariano, A., Tellechea, Óscar, & Figueiredo, A. (1). MERKEL CELL CARCINOMA – REPORT OF 7 CASES. Journal of the Portuguese Society of Dermatology and Venereology, 71(2), 171-176. https://doi.org/10.29021/spdv.71.2.166
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Original Articles