LEG ULCERS – GOOD RESPONSE TO TREATMENT WITH COLLAGEN, OXIDIZED REGENERATED CELLULOSE AND SILVER MATRIX

  • Guida Santos Interna do Internato Complementar de Dermatologia e Venereologia/ Resident of Dermatology and Venereology, Serviço de Dermatologia e Venereologia/Dermatology Department, Hospital Santo António dos Capuchos - Centro Hospitalar de Lisboa Central, Lisboa
  • Lourdes Sousa Assistente Hospitalar de Dermatologia e Venereologia/Consultant of Dermatology and Venereology, Serviço de Dermatologia e Venereologia/Dermatology Department, Hospital São Bernardo, Setúbal, Portugal
  • Alexandre João Assistente Hospitalar de Dermatologia e Venereologia/Consultant of Dermatology and Venereology, Serviço de Dermatologia e Venereologia/Dermatology Department, Hospital Santo António dos Capuchos - Centro Hospitalar de Lisboa Central, Lisboa, Portugal
Keywords: Leg ulcer, Cellulose, oxidized, Collagen, Protease inhibitors

Abstract

A greater understanding of the pathophysiology of leg ulcers has allowed the development of new therapeutic modalities. Matrices as collagen and oxidized regenerated cellulose may, by binding to proteases, lower matrix degradation, protection and stabilization of growth factors, promoting the ulcer’s healing. A 72-year-old male patient with metabolic syndrome and venous insufficiency, peripheral arterial disease, presented recalcitrant extensive and long-term ulcers, cured with dressings matrix collagen, oxidized regenerated cellulose and silver.

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Published
2014-06-24
How to Cite
Santos, G., Sousa, L., & João, A. (2014). LEG ULCERS – GOOD RESPONSE TO TREATMENT WITH COLLAGEN, OXIDIZED REGENERATED CELLULOSE AND SILVER MATRIX. Journal of the Portuguese Society of Dermatology and Venereology, 71(2), 219-223. https://doi.org/10.29021/spdv.71.2.174
Section
Case Reports