EXTRAGENITAL LICHEN SCLEROSUS IN A CHILD WITH A GOOD RESPONSE TO COLCHICINE

  • Juliana Salvini Barbosa Martins da Fonseca Médica Residente de Medicina/Resident of Internal Medicine, Hospital da Universidade Estácio de Sá - Rio de Janeiro, Brasil
  • Aline Godinho Ferreira Silva Médica Graduada de Medicina/Graduated of Internal Medicine, Universidade Iguaçu - UNIG - Itaperuna/Rio de Janeiro, Brasil
  • Mariana Gardone Guimarães Médica Residente de Medicina/Resident of Internal Medicine, Universidade Iguaçu - UNIG - Itaperuna/Rio de Janeiro, Brasil
  • Paôlla Alves de Faria Médica Residente de Medicina/Resident of Internal Medicine, Universidade Iguaçu - UNIG - Itaperuna/Rio de Janeiro, Brasil
  • Fred Bernardes Filho Pós-Graduando de Dermatologia/Graduated in Dermatology, Instituto de Dermatologia Professor Rubem David Azulay da Santa Casa da Misericórdia do Rio de Janeiro (IDPRDA / SCMRJ), Rio de Janeiro (RJ), Brasil
Keywords: Lichen sclerosus, Colchicine, Child, Skin diseases

Abstract

Lichen sclerosis is a chronic inflammatory disease of multifactorial origin involving genetic, physiological and environmental. Usually affects women between 50-60 years old, in the genital form. The pathology is uncommon in children in the extragenital form. It´s accepted as na autoimune disorder, but the mechanism remains unclear. The case report presented the flame extragenital attention as the variant form, displaying an unusual location to be affected.

We report the case of a child with extragenital form with an unusual location, femoral region. Patient made use of other medications, but had clinical improvement after the use of topical colchicine. This drug has good absorption topically and has the capacity to interrupt the mitoses of the cell. Besides that have an anti-inflammatory effect reducing mobility, adhesion and chemotaxis of polimorphonuclear cells, on the desgranulacion of lysossomes.

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Published
2014-06-24
How to Cite
Martins da Fonseca, J. S. B., Silva, A. G. F., Guimarães, M. G., Alves de Faria, P., & Filho, F. B. (2014). EXTRAGENITAL LICHEN SCLEROSUS IN A CHILD WITH A GOOD RESPONSE TO COLCHICINE. Journal of the Portuguese Society of Dermatology and Venereology, 71(2), 273-276. https://doi.org/10.29021/spdv.71.2.185
Section
Case Reports

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