PSEUDOXANTHOMA ELASTICUM-LIKE PAPILLARY DERMAL ELASTOLYSIS - A SUBDIAGNOSIS ENTITY
Abstract
Pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) is an acquired clinical entity, of unknown etiology, characterized by partial or total absence of elastic fibers in the papillary dermis. We describe the case of a 62-year-old Caucasian woman, Fitzpatrick III skin phototype, with a dermatosis characterized by multiple, asymptomatic, yellowish, monomorphic, rounded papules, with 2-3mm in diameter, located on the posterior and lateral sides of the neck with 2 years of evolution. Histopathological examination revealed a marked reduction of elastic fibres in the papillary dermis confirming PXE-PDE diagnosis. We consider that this entity, exclusively cutaneous, is under-diagnosed because it is an asymptomatic disease, in which histopathological diagnosis is difficult, if it is not clinically considered.
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References
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