MELANOTIC PIGMENTATION IN EXCISION SCARS OF MALIGNANT MELANOMA - THREE CASE REPORTS

  • Cristina Resende Interna do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Hospital de Braga, Braga, Portugal
  • Goreti Catorze Assistente Hospitalar de Dermatologia e Venereologia/Consultant Dermatology and Venereology, Hospital Egas Moniz, Lisboa, Portugal
  • Cristina Claro Assistente Hospitalar Graduada de Dermatologia e Venereologia/Graduated Consultant Dermatology and Venereology, Hospital Egas Moniz, Lisboa, Portugal
  • Isabel Viana Directora do Serviço de Dermatologia e Venereologia, Head of Department of Dermatology and Venereology, Hospital Egas Moniz, Lisboa, Portugal
DOI: https://doi.org/10.29021/spdv.73.1.354
Keywords: Skin neoplasms, Melanoma, Cicatrix

Abstract

Introduction: The appearance of pigmented lesions in scars of malignant melanoma is a finding that worries dermatologists/dermatopathologists, because they are faced with the possibility of persistence/recurrence of malignant melanoma.

Case reports: We present three cases of patients with melanocytic pigmentation in scars of malignant melanoma and discuss the clinical and histological aspects of these. In all cases, we observed macules similar to lentigo spots, but histologically we observed three different patterns: lentiginous epidermal hyperplasia, lentiginous hyperplasia of melanocytes and malignant melanoma in situ.

Discussion: There are three types of pigmentation, which may arise in the scar of malignant melanoma: lentigo type lesions, pigmented streaks and diffuse pigmentation. Histologically, three patterns of melanocytic pigmentation in scars of malignant melanoma, are described: lentiginous epidermal hyperplasia, lentiginous hyperplasia of melanocytes and persistence/ recurrence of malignant melanoma. The scar appears to be responsible for pigmentation by a process of induction acting on epidermal melanocytes.

Downloads

Download data is not yet available.

References

Botella-Estrada R, Sanmartín O, Sevila A, Escudero A, Guillén C.Melanotic pigmentation in excision scars of melanocytic and non-melanocytic skin tumors. J Cutan Pathol. 1999; 26(3):137-44.

Duve S, Schmoeckel C, Burgdorf WH. Melanocytic hyperplasia in scars. A histopathological investigation of 722 cases. Am J Dermatopathol. 1996;18(3):236-40.

Ho VC, Sober AJ. Pigmented streaks in melanoma scars. J Dermatol Surg Oncol. 1990;16(7):663-6.

Botella-Estrada R, Nagore E, Sopena J, Cremades A, Alfaro A, Sanmartín O, et al. Clinical, dermoscopy and histological correlation study of melanotic pigmentations in excision scars of melanocytic tumours. Br J Dermatol. 2006;154(3):478-84.

Massi G, LeBoit PE. Recurrent and Persistent Melanoma. In: Histological diagnosis of nevi and melanoma. Springer 2014. p.689-698.

Requena L, Yus ES, Simón P, del Rio E. Induction of cutaneous hyperplasias by altered stroma. Am J Dermatopathol. 1996;18(3):248-68.

Published
2015-06-06
How to Cite
Resende, C., Catorze, G., Claro, C., & Viana, I. (2015). MELANOTIC PIGMENTATION IN EXCISION SCARS OF MALIGNANT MELANOMA - THREE CASE REPORTS. Journal of the Portuguese Society of Dermatology and Venereology, 73(1), 127-131. https://doi.org/10.29021/spdv.73.1.354
Issue
Vol 73 No 1 (2015): Janeiro - Março
Section
Case Reports

All articles in this journal are Open Access under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).