Henoch-Schönlein Purpura (IgA Vasculitis) in Adults

  • Ana Isabel Gouveia Interna do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Clínica Universitária de Dermatologia, Hospital de Santa Maria (CHLN), Lisboa, Portugal
  • Leonor Lopes Interna do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology, Clínica Universitária de Dermatologia, Hospital de Santa Maria (CHLN), Lisboa, Portugal
  • João Pedro Freitas Assistente Hospitalar Graduado de Dermatologia e Venereologia/Graduated Consultant, Dermatology and Venereology, Clínica Universitária de Dermatologia, Hospital de Santa Maria (CHLN), Lisboa, Portugal
Keywords: Adult, Immunoglobulin A, Purpura, Schoenlein-Henoch, Vasculitis, Leukocytoclastic, Cutaneous


Henoch-Schönlein purpura is a small vessel vasculitis mediated by the deposition of IgA immune complexes. It is characterized by palpable purpura, arthralgia / arthritis, abdominal and renal involvement. Its etiology remains unknown, but various stimuli have been proposed to trigger this pathology, namely infectious agents, drugs and tumor antigens. There is also a possible association with malignancy and auto-immune diseases. Henoch-Schönlein purpura occurs mostly in children and is rare in adults. In the pediatric population the disease is generally self-limited, whereas in adults it is associated with a worse prognosis and a greater number of complications. This article reviews the main aspects of adult Henoch-Schönlein purpura, highlighting its particularities and specificities.


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How to Cite
Gouveia, A. I., Lopes, L., & Freitas, J. P. (2016). Henoch-Schönlein Purpura (IgA Vasculitis) in Adults. Journal of the Portuguese Society of Dermatology and Venereology, 74(3), 265-271. https://doi.org/10.29021/spdv.74.3.596
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