Cutaneous Disseminated Juvenile Xanthogranuloma: A Case Report

Débora Bacellar Cruz Nunes, Adriana Kamilly Leitão Pitman Machado, Michele Fonseca Goiabeira, Yandra Sherring Einecke, Alena Bacellar Cruz Nunes, Maria Amélia Lopes dos Santos, Francisca Regina Oliveira Carneiro

Abstract


Juvenile xanthogranuloma (JXG) is a benign self-limiting histiocytosis, currently classified as a disorder derived from dendrocytes and previously classified as non-Langerhans cell histiocytosis. It usually manifests as a solitary and asymptomatic lesion occurring most often in patients younger than one year of age and most cases resolve completely in three to six years, but systemic involvement may occur. The authors report a case of juvenile xanthogranuloma with an uncommon clinical presentation with disseminated lesions confirmed by the dermatoscopic, histopathologic, and immunohistochemical patterns that allowed the exclusion of possible differential diagnosis.


Keywords


Dermoscopy; Xanthogranuloma, Juvenile/diagnosis; Xanthogranuloma, Juvenile/pathology

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References


Ramos C, Cortez F, Carayhua D, Gutierrez-Ylave Z, Quijano E, et al. Multiples pápulas pardas en un adolescente. Dermatol Peru. 2012;22:50-3.

Sampaio FMS, Lourenço FT, Obadia DL, Nascimento LV. Caso para diagnóstico. An Bras Dermatol.

;87:789-90.

Díaz AA, González DN, Ruiz MT. Xantogranuloma juvenil gigante. An Pediatr. 2012; 76: 300-1.

Hertz A, Almeidinha YD, Rodrigues JB, Martins CP, Crohmal FD, et al. Xantogranuloma juvenil com múltiplas lesões. Rev Bras Med. 2014;70:16-9.

Fernandes JR, Fernandes EL, Steiner D. Aspectos dermatoscópicos do xantogranuloma juvenil com múltiplas lesões. Surg Cosmet Dermatol. 2016;8:256-8.

Alperovicha R, Grassinob PT, Asialc R, Pasterisd L, Boentea MC. Histiocitosis eruptiva generalizada-xantogranuloma juvenil: espectro clínico en un paciente pediátrico. Arch Argent Pediatr 2017;115:e116-9.

Balma-Mena A, Lara-Corrales I. Pápula rojiza, lisa y dura em antebrazo derecho. Acta Pediátr Costarric. 2010;22:57-8.

Fraile PS, Rosa JL, Badiola IA, Rey JA. Xantogranuloma juvenil de pene. Actas Urol Esp. 2008;32:659-61.

Vitral EA, Carvalho MT, Pereira CA. Xantogranuloma juvenil. An Bras Dermatol. 1995; 70:525-9.

Cheon E, Yang S, Han JH, Lee KC, Park JE. Systemic juvenile xanthogranuloma involving the bone marrow, multiple bones, and the skin that developed during treatment of acute lymphoblastic leukemia in remission state. Pediatr Dev Pathol. 2017;1:1-6. doi: 10.1177/1093526617721775.

Pretel M, Irarrazaval I, Lera M, Aguado L, Idoate MA. Dermoscopic ‘‘setting sun’’ pattern of juvenile

xanthogranuloma. Am Acad Dermatol. 2015;72(1 Suppl):S73-5. doi: 10.1016/j.jaad.2014.09.042.




DOI: http://dx.doi.org/10.29021/spdv.77.1.870

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