MYCOPHENOLATE MOFETIL FOR CHILDHOOD ATOPIC ECZEMA

Abstract

Atopic eczema is a chronic inflammatory dermatosis that affects mostly children. In most cases it can be trea- ted with topical therapy, but in a significant number of patients it is necessary to use systemic agents. In some patients side effects associated with long-term systemic treatment and insufficient therapeutic results oblige searching for new therapies. The authors describe a clinical case of a child with severe atopic eczema without a satisfactory response to prescribed therapy. Mycophenolate mofetil was started at 6 years of life, with complete resolution of inflammatory lesions at 5 months of treatment.

Therapeutic results presented in this article raise new questions about immunosuppression in atopic dermatitis and suggest a promising therapeutic alternative for cases refractory to classical treatments.
To date there is only one published study reporting the treatment with this drug in a small series of pediatric patients.

KEYWORDS – Dermatitis, Atopic; Child; Immunosuppressive Agents; Mycophenolic Acid.