Melanocytic Proliferations of Uncertain Malignant Potential: A Retrospective Study of 23 patients

  • Jorge Lopes Dermatology Department, Vila Nova de Gaia/ Espinho Hospital Center, Portugal https://orcid.org/0000-0002-8874-8296
  • Cristina Sousa Dermatology Department, Vila Nova de Gaia/ Espinho Hospital Center, Portugal
  • Diogo Teixeira Dermatology Department, Vila Nova de Gaia/ Espinho Hospital Center, Portugal
  • David Tente Pathology Department, Vila Nova de Gaia/ Espinho Hospital Center, Portugal
  • Armando Baptista Dermatology Department, Vila Nova de Gaia/ Espinho Hospital Center, Portugal
  • Ana Moreira Dermatology Department, Vila Nova de Gaia/ Espinho Hospital Center, Portugal
Palavras-chave: Lesões Pré-Cancerosas, Melanocitos, Melanoma, Neoplasias da Pele, Nevo Pigmentado

Resumo

Introdução: As lesões melanocíticas podem apresentar características histológicas que impossibilitam a sua classificação de forma dicotómica como benignas ou malignas. Estas lesões, designadas proliferações melanocíticas de potencial maligno incerto, frequentemente apresentam características limítrofes entre nevo benigno e melanoma maligno, o que reflete o seu potencial biológico indeterminado.

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Referências

Elder D, Xu X. The approach to the patient with a difficult melanocytic lesion. Pathology. 2004;36:428-34. doi: 10.1080/00313020412331283905

Pusiol T, Piscioli F, Speziali L, Zorzi MG, Morichetti D, Roncati L. Clinical features, dermoscopic patterns, and histological diagnostic model for melanocytic tumors of uncertain malignant potential (MELTUMP). Acta Derma- tovenerol Croat. 2015;23:185-94.

Abraham R, Karakousis G, Acs G, Ziober A, Cerroni L, Mihm M, et al. Lymphatic invasion predicts aggressive behavior in melanocytic tumors of uncertain malignant potential (MELTUMP). Am J Surg Pathol. 2013;37:669- 75. doi: 10.1097/PAS.0b013e318288ff47

Requena C, Requena L, Kutzner H, Yus E. Spitz nevus: a clinicopathological study of 349 cases. Am J Dermatopathol. 2009;31:107-16. doi: 10.1097/ dad.0b013e3181934218

Meyers M, Yeh J, Deal A, Byerly F, Woosley J, Frank J, et al. Age and Breslow depth are associated with a positive sentinel lymph node in patients with cutaneous melano- cytic tumors of uncertain malignant potential. J Am Coll

Surg. 2010;211:744-8. doi: 10.1016/j.jamcollsurg.

Lallas A, Kyrgidis A, Ferrara G, Kittler H, Apalla Z, Castagnetti F, et al. Atypical Spitz tumours and sentinel lymph node biopsy: a systematic review. Lancet Oncol. 2014;15:e178-83. doi: 10.1016/S1470-

(13)70608-9.

Piccolo V, Moscarella E, Lallas A, Alfano R, Fer-

rara G, Argenziano G. MELTUMP: how to ma- nage these lesions in the clinical routine. G Ital Dermatol Venereol. 2017;152:266-9. doi: 10.1016/ S1470-2045(13)70608-9

Green R, Taghizadeh R, Lewis C, Lawrence C, Husain A, Ahmed O. Melanocytic tumours of uncertain malig- nant potential (MELTUMPs) - a diagnostic and mana- gement dilemma. Eur J Plast Surg. 2014;38:13-6. doi: 10.1007/s00238-014-1028-3

Cerroni L, Barnhill R, Elder D, Gottlieb G, Heenan P, Kut- zner H, et al. Melanocytic Tumors of Uncertain Malignant Potential: results of a tutorial held at the XXIX Sympo- sium of the International Society of Dermatopathology in Graz, October 2008. Am J Surg Pathol. 2010;34:314- 26. doi: 10.1097/PAS.0b013e3181cf7fa0

Publicado
2020-01-11
Como Citar
Lopes, J., Sousa, C., Teixeira, D., Tente, D., Baptista, A., & Moreira, A. (2020). Melanocytic Proliferations of Uncertain Malignant Potential: A Retrospective Study of 23 patients. Revista Da Sociedade Portuguesa De Dermatologia E Venereologia, 77(4), 305-309. https://doi.org/10.29021/spdv.77.4.1108
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Artigos Originais