Eritema Periocular Induzido pelo Álcool: Efeito Adverso Raro de Tacrolimus

  • Loures, A Fundação Lusíada (Hospital Estadual Guilherme Álvaro), Santos- São Paulo, Brasil https://orcid.org/0000-0002-9718-6782
  • Oliveira-Soares R Hospital Cuf Descobertas, Lisboa, Portugal
Palavras-chave: Alopecia/tratamento farmacológico, Consumo de Bebidas Alcoólicas/efeitos adversos, Eritema/induzido quimicamente, Rubor//induzido quimicamente, Tacrolimus/efeitos adversos

Resumo

A crescente incidência da alopecia fibrosante frontal tornou frequente o uso tópico dos inibidores da calcineurina na região frontal para controlo da atividade da doença. Relatamos um raro efeito adverso induzido por tacrolimus e concomitante ingestão de álcool.

 

 

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Referências

Pérez-Rodríguez IM, García-Melendez ME, Eichelmann K, Vázquez-Martínez O, Ocampo-Candiani J. Hyperpigmentation following treatment of frontal fibrosing alopecia. Case reports in dermatology. 2013;5(3):357-62.

Katoulis A, Georgala S, Bozi E, Papadavid E, Kalogeromitros D, Stavrianeas N. Frontal fibrosing alopecia: treatment with oral dutasteride and topical pimecrolimus. Journal of the European Academy of Dermatology and Venereology. 2009;23(5):580-2.

Fertig R, Tosti A. Frontal fibrosing alopecia treatment options. Intractable & rare diseases research. 2016;5(4):314-5.

Carr WW. Topical calcineurin inhibitors for atopic dermatitis: review and treatment recommendations. Pediatric Drugs. 2013;15(4):303-10.

Rebora A. Tacrolimus in Asymmetric Frontal Fibrosing Alopecia. Report of A Case. Acta Scientific Microbiology. 2019;2(6):60-1.

Strazzulla LC, Avila L, Li X, Sicco KL, Shapiro J. Prognosis, treatment, and disease outcomes in frontal fibrosing alopecia: A retrospective review of 92 cases. Journal of the American Academy of Dermatology. 2018;78(1):203-5.

Ho A, Shapiro J. Medical therapy for frontal fibrosing alopecia: A review and clinical approach. Journal of the American Academy of Dermatology. 2019;81(2):568-80.

Antille C, Saurat J-H, Lübbe J. Induction of rosaceiform dermatitis during treatment of facial inflammatory dermatoses with tacrolimus ointment. Archives of dermatology. 2004;140(4):457-60.

Milingou M, Antille C, Sorg O, Saurat J-H, Lübbe J. Alcohol intolerance and facial flushing in patients treated with topical tacrolimus. Archives of dermatology. 2004;140(12):1542-4.

Stinco G, Piccirillo F, Sallustio M, Patrone P. Facial flush reaction after alcohol ingestion during topical pimecrolimus and tacrolimus treatment. Dermatology. 2008;218(1):71.

Woolner K, Sauder M. Periorbital erythema following alcohol ingestion during treatment with topical tacrolimus. CMAJ. 2016;188(5):368-.

Ohashi I, Pohoreki R, Morita K, Stemmer PM. Alcohols increase calmodulin affinity for Ca2+ and decrease target affinity for calmodulin. Biochim Biophys Acta. 2004;1691(2-3):161-7.

Kaewphaleuk T, Watanapa WB, Panich U. Ethanol enhances endothelial ionic currents and nitric oxide release via intermediate-conductance calcium-activated potassium channel. Life Sci. 2019;228:21-9.

Morales-Molina JÁ, Mateu-de J Antonio, Grau S, Ferrández ó. Alcohol ingestion and topical tacrolimus: a disulfiram-like interaction?. Ann Pharmacother. 2005; 39(4):772-3.

Publicado
2020-09-27
Como Citar
Loures, A., & Oliveira- Soares, R. (2020). Eritema Periocular Induzido pelo Álcool: Efeito Adverso Raro de Tacrolimus. Revista Da Sociedade Portuguesa De Dermatologia E Venereologia, 78(3), 269-271. https://doi.org/10.29021/spdv.78.3.1178
Secção
Casos Clínicos