Angiomatoid Spitz Nevus

Jorge Lopes; David Afonso-João; Diogo Teixeira; Armando Baptista

doi:10.29021/spdv.78.4.1245

Jorge Lopes Dermatology Department, Centro Hospitalar de Vila Nova de Gaia/ Espinho, Portugal https://orcid.org/0000-0002-8874-8296
David Afonso-João Pathology Department, Centro Hospitalar de Vila Nova de Gaia/ Espinho, Portugal https://orcid.org/0000-0003-3195-1207
Diogo Teixeira Dermatology Department, Centro Hospitalar de Vila Nova de Gaia/ Espinho, Portugal
Armando Baptista Dermatology Department, Centro Hospitalar de Vila Nova de Gaia/ Espinho, Portugal

DOI: https://doi.org/10.29021/spdv.78.4.1245

Keywords: Nevus, Epithelioid and Spindle Cell, Skin Neoplasms

Abstract

Angiomatoid Spitz nevus is a rare tumor that combines the classic aspects of Spitz nevus with a prominent vascular component. Clinically, it presents as a pink or brownish papule, usually solitary, in the extremities of young adults. On histology, it is characterized by a proliferation of epithelioid or spindle cell melanocytes embedded in a fibrous stroma, where a dense proliferation of small vessels is evident. The differential diagnosis with malignant melanoma can be difficult, particularly with the desmoplastic variant or with those with marked regression. Its behavior is benign, as suggested by the absence of local recurrences or distant metastases during long-term follow-up.

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