NECROBIOTIC XANTHOGRANULOMA ASSOCIATED WITH GIANT CELL HEPATITIS

  • Olga Ferreira Interna do Internato Complementar de Dermatologia e Venereologia/Resident, Dermatology and Venereology; Serviço de Dermatologia e Venereologia, Centro Hospitalar de São João EPE, Porto
  • Alberto Mota Assistente Hospitalar Graduado de Dermatologia e Venereologia/Graduated Consultant, Dermatology and Venereology; Serviço de Dermatologia e Venereologia, Centro Hospitalar de São João EPE, Porto
  • Teresa Baudrier Assistente Hospitalar Graduado de Dermatologia e Venereologia/Graduated Consultant, Dermatology and Venereology; Serviço de Dermatologia e Venereologia, Centro Hospitalar de São João EPE, Porto
  • Susana Rodrigues Serviço de Gastroenterologia / Gastroenterology Department, Centro Hospitalar de São João EPE, Porto
  • José Alexandre Sarmento Serviço de Gastroenterologia / Gastroenterology Department, Centro Hospitalar de São João EPE, Porto
  • José Pestana Serviço de Medicina Interna/Internal Medicine Department, Centro Hospitalar de São João EPE, Porto
  • Herberto Bettencourt Serviço de Anatomia Patológica/Pathology Department, Hospital de São João EPE, Porto, Portugal
  • Filomena Azevedo Chefe de Serviço/Directora de Serviço de Dermatologia e Venereologia/Consultant Chief, Head of Dermatology and Venereology Department, Centro Hospitalar de São João EPE, Porto, Portugal

Abstract

We describe a 44-year-old woman with recurrent episodes of red eye, myalgias, hypercholesterolemia, hypocomplementemia, monoclonal gammopathy and giant cell hepatitis that was observed due to erythematoviola- ceous plaque on the right arm. Skin biopsy revealed necrobiotic xanthogranuloma. This case illustrates the importance of accurate characterization of skin lesions in the setting of a systemic disease with difficult approach and highlights the second reported case of necrobiotic xanthogranuloma associated with giant cell hepatitis.

KEYWORDS – Necrobiotic xanthogranuloma; Giant cells; Hepatitis; Paraproteinemias.

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Published
2013-01-13
How to Cite
Ferreira, O., Mota, A., Baudrier, T., Rodrigues, S., Sarmento, J. A., Pestana, J., Bettencourt, H., & Azevedo, F. (2013). NECROBIOTIC XANTHOGRANULOMA ASSOCIATED WITH GIANT CELL HEPATITIS. Journal of the Portuguese Society of Dermatology and Venereology, 70(3), 353. https://doi.org/10.29021/spdv.70.3.13
Section
Case Reports