Fotossensibilidade Induzida por Fármacos
Resumo
A fotossensibilidade induzida por fármacos traduz uma resposta cutânea anormal à luz em indivíduos expostos a um fármaco, os quais, na sua ausência, tolerariam o mesmo grau de fotoexposição. Pode ocorrer como uma reação aguda ou retardada, assumindo características clínicas polimórficas que variam desde a queimadura solar exagerada até aspectos de fotoonicólise, pseudo- -porfíria, pigmentação, eczema agudo e lúpus eritematoso cutâneo. Os autores descrevem os fármacos mais frequentemente envolvidos neste tipo de reações e as formas clínicas mais frequentes e discutem o possível contributo destes fármacos na potenciação da fotocarcinogénese. O reconhecimento d estes padrões clínicos de fotossensibilidade e dos fármacos responsáveis é fundamental para a evicção do fármaco causal e consequente melhoria ou resolução da reação de fotossensibilidade.
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