Multiple Adult Xanthogranuloma: Case Report and Brief Literature Review

Abstract

Multiple adult xanthogranuloma is a non-Langerhans cell histiocytosis, a rare variant of the juvenile xanthogranuloma. The etiology is unknown, affecting individuals predominantly below 30 years of age, without predilection for gender. Clinically presents itself as multiple, disseminated, yellow-brownish papules or nodules. Diagnostic confirmation is given by histopathology and by immunohistochemistry, which further allow to distinguish it from Langerhans cell histiocytosis. The spontaneous regression is uncommon. We report a classic, rare and clinically exuberant case of multiple adult xanthogranuloma and took the opportunity to perform a brief literature review on the topic.