Alopecia Fibrosante em Padrão de Distribuição Androgenética: Patogénese, Diagnóstico e Tratamento

Ana Marcos-Pinto; G. De Caprio; R. Oliveira Soares

doi:10.29021/spdv.78.3.1222

Ana Marcos-Pinto Clínica Universitária de Dermatologia, Hospital de Santa Maria, Lisboa, Portugal. https://orcid.org/0000-0003-3477-0065
G. De Caprio Departamento de Dermatologia, Hospital Heliópolis- São Paulo, Brasil https://orcid.org/0000-0003-3688-0268
R. Oliveira Soares Departamento de Dermatologia, Hospital CUF Descobertas, Lisboa, Portugal

DOI: https://doi.org/10.29021/spdv.78.3.1222

Keywords: lopecia/diagnosis, Alopecia/drug therapy, Alopecia/epidemiology, Fibrosis

Abstract

Fibrosing alopecia in a pattern distribution is a recently recognized type of scarring alopecia, with hair loss in androgens- dependent area. Loss of follicular openings, perifollicular erythema, perifollicular hyperkeratosis and anisotriquia are the trichoscopic clues and follicular lichenoid inflammatory infiltrate the important finding in histopathology. It shares features of androgenetic alopecia and lichen planopilaris. Dermatologists should be familiarized with this entity in order to optimize the diagnosis and provide early treatment to prevent irreversible follicular damage.

Downloads

Download data is not yet available.

References

Zinkernagel MS, Trüeb RM. Fibrosing alopecia in a pattern distribution: patterned lichen planopilaris or androgenetic alopecia with a lichenoid tissue reaction pattern? Arch Dermatol.2000;136:205-11.

Griggs J, Trüeb RM, Gavazzoni Dias MF, Hordinsky M, Tosti A. Fibrosing alopecia in a pattern distribution. J Am Acad Dermatol. 2020 (in press). doi: 10.1016/j.jaad.2019.12.056

Piraccini BM, Alessandrini A. Androgenetic alopecia. G Ital Dermatol Venereol. 2014;149:15-24.

Kang H, Alzolibani AA, Otberg N, Shapiro J. Lichen planopilaris. Dermatol Ther.;21:249-56

Iorizzo M, Tosti A. Frontal fibrosing alopecia: an update on pathogenesis, diagnosis, and treatment. Am J Clin Dermatol. 2019;20:379-90. doi: 10.1007/s40257-019-00424-y.

Amato L, Chiarini C, Berti S, Bruscino P, Fabbri P. Case study: fibrosing alopecia in a pattern distribution localized on alopecia androgenetica areas and unaffected scalp.Skinmed. 2004;3:353-5.

Olsen EA. Female pattern hair loss and its relationship to permanent/cicatricial alopecia: a new perspective.J Investig Dermatol Symp Proc. 2005;10:217-21.

Triyangkulsri K, Srisuwanwattana P, Sriphojanart T, Suchonwanit P. Fibrosing Alopecia in a Pattern Distribution: A Case Report and Literature Review. Case Rep Dermatol. 2019;11:297-302. doi: 10.1159/000503681.

Teixeira MS, Gavazzoni Dias MF, Trüeb RM, Rochael MC, Vilar EA. Fibrosing Alopecia in a Pattern Distribution (FAPD) in 16 African-Descent and Hispanic Female Patients: A Challenging Diagnosis. Skin Appendage Disord. 2019;5:211-5. doi: 10.1159/000496837.

Bhoyrul DB. Cicatricial pattern hair loss is not a variant of lichen planopilaris. J Am Acad Dermatol. 2020 (in press). doi: 10.1016/j.jaad.2020.03.125.

Katoulis AC, Diamanti K, Sgouros D, Liakou AI, Bozi E, Avgerinou G, et al. Is there a pathogenetic link between frontal fibrosing alopecia, androgenetic alopecia and fibrosing alopecia in a pattern distribution? J Eur Acad Dermatol Venereol. 2018;32:e218-e220.

Tawfik SS, Sorour OA, Alariny AF, Elmorsy EH, Moneib H. White and yellow dots as new trichoscopic signs of severe female androgenetic alopecia in dark skin phototypes. Int J Dermatol. 2018;57:1221-8.

Missio DM, Dias MFRG, Trüeb RM. Familial Cicatricial Alopecia: Report of Familial Frontal Fibrosing Alopecia and Fibrosing Alopecia in a Pattern Distribution. Int J Trichology. 2017;9:130-4. doi: 10.4103/ijt.ijt_59_17.

Elise A. Olsen. FemalePattern Hair Loss and its Relationship to Permanent/Cicatricial Alopecia: A New Perspective. J Investig Dermatol Symp Proc. 2005; 10:217–21.

Chiu HY, Lin SJ. Fibrosing alopecia in a pattern distribution. J Eur Acad Dermatol Venereol. 2010;24:1113-4. doi: 10.1111/j.1468-3083.2010.03580.x.

Mardones F, Hott K, Martinez MC. Clinical study of fibrosing alopecia in a patterndistribution in a Latin American population. Int J Dermatol. 2018;57):e12-e14

Ramanauskaite A, Trüeb RM. Facial Papules in Fibrosing Alopecia in a Pattern Distribution (Cicatricial Pattern Hair Loss). Int J Trichology. 2015;7:119-122. 335

Billero V, Oberlin KE, Miteva M. Red dots in a net-like pattern on the upper chest:a novel clinical observation in frontal fibrosing alopecia and fibrosing alopecia in pattern distribution. Skin Appendage Disord 2018;4:47-49

Fergie B, Khaira G, Howard V, de Zwaan S. Diffuse scarring alopecia in a female pattern hair loss distr ibution. Australas J Dermatol. 2018;59:e43-e46

De Mozzi P, Crichlow SM, Da Forno PD, Alexandroff B. A case report of fibrosing 359 alopecia in a female pattern distribution. G Ital Dermatol Venereol. 2013;148:710-11.

Mancini I, Rotilio A, Coati I, Seracchioli R, Martelli V, Meriggiola MC. Presentation of a meningioma in a transwoman after nine years of cyproterone acetate and estradiol intake: case report and literature review. Gynecol Endocrinol. 2018;34:456-9. doi: 10.1080/09513590.2017.1395839.