ACTINIC GRANULOMA OF O’BRIEN – RESPONSE TO GRISEOFULVIN

  • Carolina Pelegrin Tonin Médica Estagiária do Serviço de Dermatologia/Student, Dermatology, Faculdade de Medicina do ABC-São Paulo (SP), Brasil
  • Claudia De Nadai Pereira Médica Residente em Dermatologia/Resident, Dermatology, Faculdade de Medicina do ABC-São Paulo (SP), Brasil
  • Flávia Cury Rezende Médica Residente em Dermatologia/Resident, Dermatology, Faculdade de Medicina do ABC-São Paulo (SP), Brasil
  • Nobuo Matsunaga Médico Dermatologista/Dermatologist, Faculdade de Medicina do ABC-São Paulo (SP), Brasil
  • Gilles Landman Médico Dermatopatologista/Dermatopathologist, Serviço de Dermatologia da Faculdade de Medicina do ABC-São Paulo (SP), Brasil
  • Carlos D'Apparecida Machado Fillo Médico Dermatologista, Chefe da Disciplina de Dermatologia/Dermatologist, Professor of Dermatology, Faculdade de Medicina do ABC-São Paulo (SP), Brasil
DOI: https://doi.org/10.29021/spdv.73.4.492
Keywords: Granuloma, Giant Cell, Griseofulvin

Abstract

Actinic granuloma of O’Brien, also called annular elastolytic giant cell granuloma is a rare condition. It shows clinically as papules lesions that converge in annular plaques lesions with an atrophic center. Histologically, it evidences elastophagocytosis and elastolysis. The case below describes a female patient, 53 years old, that had classical clinical and histopathological lesions of actinic granuloma that showed a significant improvement upon the introduction of adjunctive griseofulvin therapy.

Downloads

Download data is not yet available.

References

Lazzarini R, Rotter A, Farias DC, Muller H. Granuloma actínico de O’Brien: apresentação clínica exuberante. An Bras Dermatol. 2011;86:339-42.

Gonçalvez RR, Miranda MF, Viana FO, Cavaleiro LH, Fonseca DM. Granuloma anular elastolítico gigantocelular: relato de caso. An Bras Dermatol. 2011;86.

Machado Filho CD, faltam autores et al. Granuloma anular elastolítico de células gigantes. Med Cutan Iber Lat Am. 2007;35:156-8.

Muñoz LC, Díaz-Díaz RM, Quesada-Cortés A, Hernández-Cano N, Martín-Díaz MA, Regojo-Zapata RM, et al. Granuloma elastolítico anular de células gigantes: a propósito de un caso localizado en áreas no fotoexpuestas. Actas Dermosifiliogr. 2006; 97:533-5.

Panzarelli A, Camejo O. Granuloma anular elastolítico de células gigantes com buena respuesta a dapsona. Dermatol Venezolana. 2001; 39:27-9.

Ratnavel RC, Grant JW, Handfield-Jones SE, Norris PG. O'Brien's actinic granuloma:response to isotretinoin. J R Soc Med. 1995;88:528-9.

Gregoris JA, Monti JA, Lizarraga V. Granuloma actinico de O'Brien. Rev Argent Dermatol. 2009; 90:86-90.

Nico MMS, Fernandes JD, Lourenço SV. Líquen plano oral. An Bras Dermatol. 2011; 86:633-43.

Watanabe S, Tanaka M, Kobayashi K, Sawada M, Ishizaki S, Tsurui K, et al. Remission of generalized erythematous granuloma annulare after improvement of hyperlipidemia and review of the Japanese literature. Dermatol Pract Concept. 2014;4:97-100.

Published
2016-01-28
How to Cite
Pelegrin Tonin, C., De Nadai Pereira, C., Cury Rezende, F., Matsunaga, N., Landman, G., & D’Apparecida Machado Fillo, C. (2016). ACTINIC GRANULOMA OF O’BRIEN – RESPONSE TO GRISEOFULVIN. Journal of the Portuguese Society of Dermatology and Venereology, 73(4), 489-492. https://doi.org/10.29021/spdv.73.4.492
Issue
Vol 73 No 4 (2015): Outubro - Dezembro
Section
Case Reports

All articles in this journal are Open Access under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).