OMALIZUMAB IN SEVERE ATOPIC DERMATITIS

  • Sofia Luz Serviço de Imunoalergologia do Centro Hospitalar Lisboa Norte, Hospital de Santa Maria
  • Pedro Silva Serviço de Imunoalergologia do Centro Hospitalar Lisboa Norte, Hospital de Santa Maria
  • Ana Célia Costa Serviço de Imunoalergologia do Centro Hospitalar Lisboa Norte, Hospital de Santa Maria
  • Amélia Spínola Santos Serviço de Imunoalergologia do Centro Hospitalar Lisboa Norte, Hospital de Santa Maria
  • Elisa Pedro Serviço de Imunoalergologia do Centro Hospitalar Lisboa Norte, Hospital de Santa Maria
  • Manuel Pereira Barbosa Serviço de Imunoalergologia do Centro Hospitalar Lisboa Norte, Hospital de Santa Maria
Keywords: Omalizumab, Severe atopic dermatitis

Abstract

We present the cases of two young females with severe atopic dermatitis, treated with anti-histamines, topical corticosteroids, high-dose systemic corticosteroids bursts and/or oral cyclosporine, without significant improvement and worsening with tapering of corticosteroids and/or cyclosporine. Several therapeutical adjustments were made without success before starting treatment with subcutaneous omalizumab. The clinical evolution of these patients undergoing treatment with omalizumab is described and its role in the treatment of atopic dermatitis is discussed.

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Published
2011-06-23
How to Cite
Luz, S., Silva, P., Costa, A. C., Spínola Santos, A., Pedro, E., & Pereira Barbosa, M. (2011). OMALIZUMAB IN SEVERE ATOPIC DERMATITIS. Journal of the Portuguese Society of Dermatology and Venereology, 69(2), 267-271. https://doi.org/10.29021/spdv.69.2.615
Section
Case Reports

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