Sweet Syndrome and HIV Infection: What We Can Interpret?

  • Pedro Paulo Coutinho Médico residente em dermatologia, Fundação de Medicina Tropical-Doutor Heitor Vieira Dourado (FMT-HVD), Manaus, Amazonas, Brasil
  • Amanda Araújo de Moura Médico residente em dermatologia, Fundação de Medicina Tropical-Doutor Heitor Vieira Dourado (FMT-HVD), Manaus, Amazonas, Brasil
  • Bruno de Castro e Souza Médico residente em dermatologia, Hospital do Servidor Público Estadual de São Paulo, São Paulo
  • Bruno Vianei Real António Estudante de Medicina da Universidade Federal do Amazonas (UFAM), Manaus, Amazonas, Brasil
  • Raquel Rodrigues Ferreira Rocha de Alencar Estudante de Medicina da Universidade Federal do Amazonas (UFAM), Manaus, Amazonas, Brasil
  • Fábio Francesconi do Valle Médico dermatologista, especialista pela Sociedade Brasileira de Dermatologia (SBD), chefe do serviço de residência médica em dermatologia da Fundação de Medicina Tropical-Doutor Heitor Vieira Dourado (FMT-HVD), Manaus, Amazonas, Brasil
Keywords: Antiretroviral Therapy, Highly Active, HIV Infections, Immune Reconstitution Inflammatory Syndrome, Sweet Syndrome

Abstract

Sweet's syndrome is a neutrophilic dermatosis whose etiopathogenesis is not yet fully known. Histopathology of cutaneous lesions shows an infiltrate with mature neutrophils diffusely distributed in the papillary dermis. The diagnosis is made through clinical, laboratory and histopathological criteria. Association of Sweet syndrome and HIV infection is scarcely related in the literature, having been reported with the use of abacavir, opportunistic infections and vaccination. The explicit evidence for the association is considering Sweet's syndrome as a manifestation of immune reconstitution syndrome, which occurs in 10% to 45% of HIV-infected individuals at the start of antiretroviral therapy. The present report describes the case of a patient HIV-positive for 4 years, who maintained antiretroviral therapy irregularity and, after regularizing the use of antiretrovirals, developed Sweet syndrome.

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Author Biography

Pedro Paulo Coutinho, Médico residente em dermatologia, Fundação de Medicina Tropical-Doutor Heitor Vieira Dourado (FMT-HVD), Manaus, Amazonas, Brasil
Serviço de Residência Médica em Dermatologia da Fundação de Medicina Tropical Dr Heitor Vieira Dourado

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Published
2018-12-27
How to Cite
Coutinho, P. P., Araújo de Moura, A., de Castro e Souza, B., Real António, B. V., Rocha de Alencar, R. R. F., & Francesconi do Valle, F. (2018). Sweet Syndrome and HIV Infection: What We Can Interpret?. Journal of the Portuguese Society of Dermatology and Venereology, 76(4), 439-444. https://doi.org/10.29021/spdv.76.4.931
Section
Case Reports