Fotodermatoses Autoimunes Parte I - Fisiopatologia e Diagnóstico

  • Virginia Coelho de Sousa Serviço de Dermatologia, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisboa, Portugal
  • Rita Ramos Pinheiro Serviço de Dermatologia, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisboa, Portugal
  • Filipa Rocha Páris Serviço de Dermatologia, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisboa, Portugal
  • Margarida Apetato Serviço de Dermatologia, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisboa, Portugal
  • Gabriela Marques Pinto Serviço de Dermatologia, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisboa, Portugal
Palavras-chave: Dermatite Fotoalérgica/diagnóstico, Dermatite Fotoalérgica/etiologia, Perturbações de Fotossensibilidade/ diagnóstico, Perturbações de Fotossensibilidade/etiologia, Raios Ultravioleta, Sistema Imunológico

Resumo

As fotodermatoses autoimunes constituem um grupo heterogéneo de dermatoses idiopáticas que têm na sua génese alterações imunológicas atualmente não completamente esclarecidas. Este grupo inclui cinco entidades clinicamente distintas - erupção polimorfa à luz, prurigo actínico, hydroa vacciniforme, dermite actínica crónica, urticária solar -, algumas potencialmente graves e com grande impacto na qualidade de vida dos doentes. A fisiopatologia das fotodermatoses autoimunes parece estar relacionada com a formação de fotoalergénios em respota à exposição solar. O mecanismo de reação de hipersensibilidade é variável entre as diferentes patologias. O diagnóstico das fotodermatoses autoimunes depende do reconhecimento das caraterísticas clínicas. A realização de fototestes permite a confirmação do diagnóstico e a determinação da radiação e dose limiar indutora. Numa altura em que a área da fotodermatologia tem vindo a perder gradualmente o seu impacto, propomos rever a fisiopatologia e abordagem diagnóstica atual das fotodermatoses autoimunes.

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Publicado
2018-01-26
Como Citar
Coelho de Sousa, V., Ramos Pinheiro, R., Rocha Páris, F., Apetato, M., & Marques Pinto, G. (2018). Fotodermatoses Autoimunes Parte I - Fisiopatologia e Diagnóstico. Revista Da Sociedade Portuguesa De Dermatologia E Venereologia, 75(4), 357-368. https://doi.org/10.29021/spdv.75.4.876
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